GlucoKinaseDB
Manually curated database of 1,700+ glucokinase modulators with bioactivity and chemical data, in-browser 3D structure visualization, and API endpoints.
the problem#
Glucokinase is a glucose sensor in the liver and pancreas, and a long-standing drug target for type 2 diabetes. The catch is that data on its modulators, the activators, inhibitors, and GK-GKRP disruptors, sits scattered across papers, patents, and chemical repositories. GlucoKinaseDB pulls it into one place, with bioactivity and chemical detail on every entry.
- modulators
- 1,700+
- classes
- GKAs, GKIs, GK-GKRP disruptors
- per entry
- bioactivity, structure, descriptors
- sources
- literature, patents, repositories
what I built#
I built the platform end to end: the web app, its MySQL database, in-browser 3D structure viewing with 3Dmol.js, sortable data tables, and a small API so the data is reachable from Python or R. Every entry links back to its source and out to PubChem and ChEMBL.
## skills
- databases
- dataviz
- web dev